Anxiolytic and antidepressant effects of cannabidiol: a systematic review

Autores/as

  • José Eduardo Ribeiro Honório Júnior Professor of the Biomedicine Course at Centro Universitário Christus (UNICHRISTUS) and Coordinator of the Unichristus translational neuroscience lab, Campus Parque Ecológico, Fortaleza, Ceará, Brazil. https://orcid.org/0000-0001-8320-8525
  • Jessica Rodrigues de Morais Barriga Biomedical formed by the Centro Universitário Christus (UNICHRISTUS), Campus Parque Ecológico, Fortaleza, Ceará, Brazil.
  • Dara da Silva Mesquita Master's Student of the Master's Course in Translational Medicine at the Federal University of Ceará (UFC), Campus Porangabuçu, Fortaleza, Ceará, Brazil.
  • Joel Porfírio Pinto Professor of the Psychology Course at the University of Fortaleza (UNIFOR) and psychologist of the hospital of mental health Professor Frota Pinto Fortaleza, Ceará, Brazil https://orcid.org/0000-0001-6084-7818

DOI:

https://doi.org/10.12662/2317-3076jhbs.v9i1.3366.p1-7.2021

Palabras clave:

Cannabis, Cannabidiol, Anxiolytic, Antidepressant

Resumen

Objetctive: Realize a systematic review on articles about cannabidiol (CBD) as an anxiolytic and antidepressant drug. Methodology: A systematic review in PubMed, Science Direct and PsycINFO databases taking into consideration articles published in English and Portuguese from 2008 to 2018 with animal experimentation. Results: Eleven articles with experimental studies on animals were included. All studies exhibited anxiolytic and antidepressant activities after CBD use. Conclusion: It was proven by several experiments the anxiolytic and antidepressant activity of CBD, however there is still a need of more preclinicals and clinicals studies to elucidate its mechanisms.

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Publicado

2021-04-06

Cómo citar

1.
Honório Júnior JER, Barriga JR de M, Mesquita D da S, Pinto JP. Anxiolytic and antidepressant effects of cannabidiol: a systematic review. J Health Biol Sci. [Internet]. 6 de abril de 2021 [citado 27 de junio de 2025];9(1):1-7. Disponible en: https://unichristus.emnuvens.com.br/jhbs/article/view/3366

Número

Vol. 9 Núm. 1 (2021): Journal of Health and Biological Sciences

Sección

ARTÍCULOS DE REVISIÓN

Licencia

Derechos de autor 2021 Journal of Health and Biological Sciences

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.

Creative Commons License