Lucio's phenomenon presenting as retiform purpura and diffuse cutaneous necrosis with a fatal outcome

a case report

Authors

DOI:

https://doi.org/10.12662/2317-3076jhbs.v14i1.5722.pe5722.2026

Keywords:

Lucio's phenomenon, leprosy, retiform purpura, cutaneous necrosis

Abstract

Lucio's phenomenon is a rare and severe leprosy-associated reaction, characterized by erythema, painful macules, and hemorrhagic bullae that progress to ulcerations. This case report details a patient with leprosy complicated by Lucio's phenomenon, where delayed diagnosis and treatment contributed to a fatal outcome. The report underscores the critical importance of early diagnosis and prompt intervention to prevent severe complications and improve clinical outcomes.

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Author Biographies

Orivaldo Alves Barbosa, Hospital Geral Doutor Cesar Cals

Possui graduação em Medicina pela Universidade Federal do Ceará (2010). , atuando principalmente nos seguintes temas: kidney transplantation, histoplasmosis,

amiloidose renal, immunosupression e hanseniase.

Residencia Medica em Clnica Medica pelo HGCC

Preceptor do servico de Clinica medica do HGCC

Professor do centro universitario Christus ( UNICHRISTUS)

Sergio Saldanha Freire Simões, Hospital Geral Doutor Cesar Cals

Internal Medicine Medical Resident In General Hospital Dr. César Cals

Francisco Tomaz da Costa Filho, Hospital Geral Doutor Cesar Cals

Internal Medicine Medical Resident In General Hospital Dr. César Cals

José Walter Correia, Hospital Geral Doutor Cesar Cals

MD , Phd , Cesar Cals Hospital

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Published

2026-01-22

How to Cite

1.
Barbosa OA, Saldanha Freire Simões S, Coutinho de Araújo Macedo AL, da Costa Filho FT, Walter Correia J, Aguiar de Freitas K, et al. Lucio’s phenomenon presenting as retiform purpura and diffuse cutaneous necrosis with a fatal outcome: a case report. J Health Biol Sci. [Internet]. 2026 Jan. 22 [cited 2026 May 27];14(1):e5722. Available from: https://unichristus.emnuvens.com.br/jhbs/article/view/5722

Issue

Vol. 14 No. 1 (2026): Journal of Health and Biological Sciences

Section

Case Report

License

Copyright (c) 1969 Orivaldo Alves Barbosa, Sergio Saldanha Freire Simões, Andre Luis Coutinho de Araújo Macedo, Francisco Tomaz da Costa Filho, Karina Aguiar de Freitas, José Walter Correia, Eliseu Sousa do Amaral Júnior

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Creative Commons License