A relação do transtorno do espectro autista e a disbiose intestinal: uma revisão integrativa

Authors

DOI:

https://doi.org/10.12662/2317-3076jhbs.v10i1.4201.p1-9.2022

Keywords:

Transtorno do Espectro Autista, Microbiota gastrointestinal, Disbiose intestinal

Abstract

Objetivos: evidenciar as relações e a existência do agravamento do Transtorno do Espectro Autista devido à disbiose intestinal. Métodos: revisão integrativa realizada segundo a pergunta norteadora: Existe comprovação científica entre a relação do TEA e disbiose intestinal que favoreça a melhora na prática clínica e indicações de possíveis respostas? Buscou-se por artigos publicados entre janeiro de 2016 e janeiro de 2021, nas bases de dados: PubMed, SciELO, LILACS, GOOGLE ACADÊMICO. Foram utilizados os descritores (DeCS): “Transtorno do Espectro Autista”; “Microbiota gastrointestinal”; “Disbiose”, associados pelo operador booleano “E”. Foram incluidos artigos de revisões bibliográficas, completos, originais, limitados aos idiomas inglês e português brasileiro, publicados nos últimos cinco anos, e que, após leitura do resumo, estivessem dentro do escopo da revisão. Resultados: Foram identificados 52 manuscritos e, após aplicação dos critérios de inclusão e exclusão, foram considerados 11 artigos que evidenciam o agravamento do TEA por fatores intrínsecos à microbiota intestinal. Conclusão: existe importante influência causal do eixo bidirecional cérebro-intestino-microbiota na etiologia e exacerbaçao das manifestações clínicas do Transtorno do Espectro Autista devido à disbiose intestinal e aos fatores gastrointestinais de origem idiopática.

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Published

2022-12-30

How to Cite

1.
Sabino SM do V, Belém M de O. A relação do transtorno do espectro autista e a disbiose intestinal: uma revisão integrativa. J Health Biol Sci. [Internet]. 2022 Dec. 30 [cited 2024 Dec. 23];10(1):1-9. Available from: https://unichristus.emnuvens.com.br/jhbs/article/view/4201

Issue

Vol. 10 No. 1 (2022): Journal of Health and Biological Sciences

Section

Review Articles

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