Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment

Authors

  • Italo Gustavo Lima Monteiro Hospital Universitário Walter Cantídeo (HUWC)
  • Luis Arthur Brasil Gadelha Farias Universidade Federal do Ceará (UFC)
  • Ruth Maria Oliveira de Araújo Hospital Universitário Walter Cantídeo (HUWC)
  • Licia Borges Pontes Hospital Universitário Walter Cantídeo (HUWC) Centro Universitário Christus (UNICHRISTUS)

DOI:

https://doi.org/10.12662/2317-3076jhbs.v9i1.3545.p%25p.2021

Keywords:

Mucormycosis, Amphotericin B, Liposomal Formulation,  Drug Therapy

Abstract

Introduction: Mucormycosis is an infection caused by the ubiquitous saprophyte fungi with rapid and aggressive progression, especially in immunocompromised patients. Case report: A 57-year-old woman diagnosed with rhino-orbital mucormycosis presented with decreased renal function after treatment with amphotericin B deoxycholate which was discontinued. Renal function improved after amphotericin B lipid-complex, being also treated with itraconazole, and otorhinolaryngological surgery. Conclusion: The use of Amphotericin B deoxycholate may result in adverse effects. In this situation, Amphotericin B lipid formulation is usually the drug of choice.

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Author Biography

Luis Arthur Brasil Gadelha Farias, Universidade Federal do Ceará (UFC)

Graduando em Medicina pela Universidade Federal do Ceará (UFC), com previsão de conclusão em 2019. Atualmente, encontra-se vinculado à IFMSA- Brazil, onde exerce a função de LVPE- Local Vice- President for external affairs no comitê UFC-Fortaleza. É monitor de Parasitologia Médica na Universidade Federal do Ceará e Membro ativo da Liga de Estudos e Ações em Doenças Infecciosas - LEDI.

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Published

2021-06-07

How to Cite

1.
Monteiro IGL, Farias LABG, de Araújo RMO, Pontes LB. Rhino-orbital mucormycosis in a diabetes patient with renal impairment after amphotericin B deoxycholate: the role of amphotericin B lipid-complex treatment. J Health Biol Sci. [Internet]. 2021 Jun. 7 [cited 2025 Jun. 27];9(1):1-4. Available from: https://unichristus.emnuvens.com.br/jhbs/article/view/3545

Issue

Vol. 9 No. 1 (2021): Journal of Health and Biological Sciences

Section

Case Report

License

Copyright (c) 2021 Journal of Health & Biological Sciences

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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