Anxiolytic and antidepressant effects of cannabidiol: a systematic review

Autores

  • José Eduardo Ribeiro Honório Júnior Christus University Center https://orcid.org/0000-0001-8320-8525
  • Jessica Rodrigues de Morais Barriga Biomedical formed by the Centro Universitário Christus (UNICHRISTUS), Campus Parque Ecológico, Fortaleza, Ceará, Brazil.
  • Dara da Silva Mesquita Master's Student of the Master's Course in Translational Medicine at the Federal University of Ceará (UFC), Campus Porangabuçu, Fortaleza, Ceará, Brazil.
  • Joel Porfírio Pinto Professor of the Psychology Course at the University of Fortaleza (UNIFOR) and psychologist of the hospital of mental health Professor Frota Pinto Fortaleza, Ceará, Brazil https://orcid.org/0000-0001-6084-7818

DOI:

https://doi.org/10.12662/2317-3076jhbs.v9i1.3366.p1-7.2021

Palavras-chave:

Cannabis, Cannabidiol, Anxiolytic, Antidepressant

Resumo

Objetctive: Realize a systematic review on articles about cannabidiol (CBD) as an anxiolytic and antidepressant drug. Methodology: A systematic review in PubMed, Science Direct and PsycINFO databases taking into consideration articles published in English and Portuguese from 2008 to 2018 with animal experimentation. Results: Eleven articles with experimental studies on animals were included. All studies exhibited anxiolytic and antidepressant activities after CBD use. Conclusion: It was proven by several experiments the anxiolytic and antidepressant activity of CBD, however there is still a need of more preclinicals and clinicals studies to elucidate its mechanisms.

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Publicado

2021-04-06

Como Citar

1.
Honório Júnior JER, Barriga JR de M, Mesquita D da S, Pinto JP. Anxiolytic and antidepressant effects of cannabidiol: a systematic review. J Health Biol Sci. [Internet]. 6º de abril de 2021 [citado 27º de junho de 2025];9(1):1-7. Disponível em: https://unichristus.emnuvens.com.br/jhbs/article/view/3366

Edição

v. 9 n. 1 (2021): Journal of Health and Biological Sciences

Seção

Artigos de Revisão

Licença

Copyright (c) 2021 José Eduardo Ribeiro Honório Júnior, Jessica Rodrigues de Morais Barriga, Dara da Silva Mesquita, Joel Porfírio Pinto

Creative Commons License

Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial 4.0 International License.